Dendrimer-Derived Mimics of Host Defense Peptides Selectively Disrupt Cancer Cell Membranes for Melanoma Therapy

Dendrimer-Derived Mimics of Host Defense Peptides Selectively Disrupt Cancer Cell Membranes for Melanoma Therapy

<b>Background</b>: Melanoma is one of the most common malignancies, posing a significant health threat to patients, particularly in advanced stages due to its high aggressiveness. Chemotherapy agents with biocompatibility and low susceptibility to induce resistance are required for syste...

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Bibliographic Details
Main Authors: Yusheng Qian, Danjing Yang, Xiangyu Lin, Chenyun Shen, Jieping Zhang, Jin Xu, Yan Zhao, Ling Zhu, Haoran Kong, Mingyu Zhang, Yueqian Zhu, Chuncai Zhou, Jing He
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceutics
Subjects:
host defense peptides
melanoma
anticancer polymers
membranolytic mechanism
Online Access:https://www.mdpi.com/1999-4923/17/3/361
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