Novel Epigenetics Control (EpC) Nanocarrier for Cancer Therapy Through Dual-Targeting Approach to DNA Methyltransferase and Ten-Eleven Translocation Enzymes

Background/Objectives: Aberrant hypermethylation in the promoter regions of tumor suppressor genes facilitates the pathogenesis and progression of cancer. Therefore, inhibitors targeting DNA methyltransferase (DNMT) have been tested in clinical studies. However, the current monotherapy of DNMT inhib...

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Bibliographic Details
Main Authors: Risa Mitsuhashi, Kiyoshi Sato, Hiroyoshi Kawakami
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Epigenomes
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Online Access:https://www.mdpi.com/2075-4655/9/1/6
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