Diagnostic Utility of Podoplanin Immunohistochemistry Combined with the NanoSuit-Correlative Light and Electron Microscopy Method for Thoracic Malignant Tumors

Diagnostic Utility of Podoplanin Immunohistochemistry Combined with the NanoSuit-Correlative Light and Electron Microscopy Method for Thoracic Malignant Tumors

<b>Background/Objectives:</b> Differentiating thoracic malignant tumors, such as epithelioid malignant pleural mesothelioma (EMPM) and non-small-cell lung carcinoma (NSCLC), primarily comprising lung adenocarcinoma (LAC) and lung squamous cell carcinoma (LSCC), remains a challenge in rou...

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Main Authors: Shin-ya Katsuragi, Yuri Sakano, Isao Ohta, Hisami Kato, Rei Ishikawa, Hirofumi Watanabe, Ryosuke Miyazaki, Katsuhiro Yoshimura, Hidetaka Yamada, Yasuhiro Sakai, Yusuke Inoue, Yusuke Takanashi, Keigo Sekihara, Kazuhito Funai, Yoshiro Otsuki, Hideya Kawasaki, Kazuya Shinmura
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Diagnostics
Subjects:
epithelioid malignant pleural mesothelioma (EMPM)
lung adenocarcinoma (LAC)
lung squamous cell carcinoma (LSCC)
microvilli
NanoSuit-correlative light and electron microscopy (CLEM) method
non-small-cell lung carcinoma (NSCLC)
Online Access:https://www.mdpi.com/2075-4418/15/10/1298
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