The Early Response After Radiation Therapy on Three-Dimensional Oral Cancer Model Using Patient-Derived Cancer-Associated Fibroblasts

The Early Response After Radiation Therapy on Three-Dimensional Oral Cancer Model Using Patient-Derived Cancer-Associated Fibroblasts

<b>Background/Objectives:</b> Cancer-associated fibroblasts (CAFs), which are an important component of the tumor microenvironment, have been reported to have an adverse effect on conventional radiotherapy. This study aims to elucidate the effects of CAFs in boron neutron capture therapy...

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Bibliographic Details
Main Authors: Izumi Yamamoto, Kazuyo Igawa, Natsuko Kondo, Yoshinori Sakurai, Atsushi Fujimura, Kiyofumi Takabatake, Peng Huang, Hiroyuki Michiue, Soichiro Ibaragi, Kenji Izumi
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:International Journal of Translational Medicine
Subjects:
3D model
oral cancer
patient-derived cells
cancer-associated fibroblasts
radiation treatment
boron neutron capture therapy
Online Access:https://www.mdpi.com/2673-8937/5/1/12
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