Chemoproteogenomic stratification of the missense variant cysteinome

Chemoproteogenomic stratification of the missense variant cysteinome

Abstract Cancer genomes are rife with genetic variants; one key outcome of this variation is widespread gain-of-cysteine mutations. These acquired cysteines can be both driver mutations and sites targeted by precision therapies. However, despite their ubiquity, nearly all acquired cysteines remain u...

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Main Authors: Heta Desai, Katrina H. Andrews, Kristina V. Bergersen, Samuel Ofori, Fengchao Yu, Flowreen Shikwana, Mark A. Arbing, Lisa M. Boatner, Miranda Villanueva, Nicholas Ung, Elaine F. Reed, Alexey I. Nesvizhskii, Keriann M. Backus
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53520-x
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https://doi.org/10.1038/s41467-024-53520-x

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