DNA damage response factors from diverse pathways, including DNA crosslink repair, mediate alternative end joining.

Alternative end joining (Alt-EJ) chromosomal break repair involves bypassing classical non-homologous end joining (c-NHEJ), and such repair causes mutations often with microhomology at the repair junction. Since the mediators of Alt-EJ are not well understood, we have sought to identify DNA damage r...

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Bibliographic Details
Main Authors: Sean M Howard, Diana A Yanez, Jeremy M Stark
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004943&type=printable
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