Necroptosis in vascular cognitive impairment: mechanisms and therapeutic potential

Cerebral ischemia and hypoxia play key roles in the occurrence and development of vascular cognitive impairment (VCI). However, the pathophysiology of VCI remains unclear. Necroptosis is a non-cysteine-dependent form of cell death mediated by serine/threonine kinases receptor-interacting protein kin...

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Main Authors: Shufei Wei, Lin Cheng, Chunxiao Shen, Zefen Li, Jiahui Teng, Liangliang Wang, Xiaorong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Aging Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2025.1599773/full
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