Evolution of cetacean-specific conserved non-coding elements suggests their role in the limb changes during secondary aquatic adaptation

Evolution of cetacean-specific conserved non-coding elements suggests their role in the limb changes during secondary aquatic adaptation

Abstract Background Limb morphology is particularly important for animals to inhabit different environments. Limb modifications (e.g., flipper-like forelimbs and hindlimb regression) are among the most critical secondary aquatic adaptation mechanisms enabling cetaceans to fully adapt to an aquatic e...

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Bibliographic Details
Main Authors: Zhenhua Zhang, Zhenpeng Yu, Yujie Chong, Yao Liu, Jia Liu, Wenhua Ren, Shixia Xu, Guang Yang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Biology
Subjects:
Cetaceans
Limb morphology
CNEs
Transgenic mice
Phenotypic recovery
Online Access:https://doi.org/10.1186/s12915-025-02300-0
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https://doi.org/10.1186/s12915-025-02300-0

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