Prolonged postnatal adaptation and enhanced prevalence of congenital heart diseases due to altitude may contribute to newborn mortality in Bolivia

Prolonged postnatal adaptation and enhanced prevalence of congenital heart diseases due to altitude may contribute to newborn mortality in Bolivia

Abstract Highland populations suffer from significant infant mortality due to chronic ambient hypoxia, which increases the risk of congenital heart disease (CHD) and neonatal pulmonary hypertension. Neither the prevalence of these conditions nor the effectiveness of neonatal cardiac screening to ide...

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Main Authors: Alexandra Heath, Inge vonAlvensleben, Jesús Ardiles Spielvogel, Pablo Freudenthal, Johannes Trapp, Ivanna Noya, Miguel Gálvez, Fanny Mendizábal, Mariana Gonzales, Ceylan Apaza, Leibniz Sanga, Erin Mc Cann, Colleen G. Julian
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Experimental Physiology
Subjects:
cardiopulmonary transition
congenital heart disease
high altitude
hypoxia
oxygen dependency
pulmonary hypertension
Online Access:https://doi.org/10.1113/EP092215
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https://doi.org/10.1113/EP092215

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