Bromelain prevents Alzheimer's disease progression by suppressing oxidative stress and upregulating apolipoprotein A1 in 5x familial Alzheimer's disease transgenic mice

Alzheimer's disease (AD), a devastating neurodegenerative disorder, is the most prevalent form of dementia. The pathological hallmark of AD is the accumulation of β-amyloid (Aβ) in the hippocampus and cerebral cortex, leading to oxidative stress, neuronal death, and brain atrophy. Bromelain, a...

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Main Authors: Julia Chu-Ning Hsu, Po-An Hu, Chia-Hui Chen, Chia-Ju Lee, Hsuan-Yun Hu, Man-Chen Hsu, Wen-Hua Chen, Hsueh-Te Lee, Tzong-Shyuan Lee
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Journal of Agriculture and Food Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666154325002984
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