Cost-Effectiveness analysis of the 21-Gene platform for guiding treatment decisions for early Hormone-Positive breast cancer: the perspective of the Brazilian public health system

Abstract Introduction The 21-gene platform Oncotype DX helps clinicians identify women with early- stage estrogen receptor (ER)-positive breast cancer who will not benefit from adjuvant chemotherapy. However, it is too expensive to be implemented by the Brazilian public health system (SUS). Therefor...

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Main Authors: Daniel de Iracema Gomes Cubero, Fernando Luiz Affonso Fonseca, Beatriz da Costa Aguiar Alves Reis, Luiz Vinicius de Alcantara Sousa, Jean Henri Maselli-Schoueri, Auro da Giglio
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Health Services Research
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Online Access:https://doi.org/10.1186/s12913-025-13230-6
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