Medulloblastoma’s master regulators and their association with patients’ risk

Medulloblastoma’s master regulators and their association with patients’ risk

Abstract Medulloblastoma (MB) is the most common malignant pediatric brain tumor, accounting for approximately 20% of all childhood brain tumors. Despite recent advances, current treatments like surgery, radiation, and chemotherapy still lead to severe side effects and high morbidity. Limited knowle...

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Main Authors: Gustavo Lovatto Michaelsen, Tayrone de Sousa Monteiro, Danilo Oliveira Imparato, João Vitor Almeida da Costa, Daniel Rocha Silva, Iara Dantas de Souza, Marcel Câmara da Ribeiro-Dantas, Otávio Cabral-Marques, Marialva Sinigaglia, Rodrigo Juliani Siqueira Dalmolin
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Medulloblastoma
Transcription factor
Regulome
Systems biology
Online Access:https://doi.org/10.1038/s41598-025-00763-3
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https://doi.org/10.1038/s41598-025-00763-3

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