Discovery of glycerol phosphate and an immunogenic glycan motif in rhamnose-rich polysaccharides of Streptococcus uberis

Discovery of glycerol phosphate and an immunogenic glycan motif in rhamnose-rich polysaccharides of Streptococcus uberis

Abstract Streptococcus uberis is a causative pathogen of bovine mastitis with high genetic diversity. Rhamnose-rich polysaccharides (RPS) are abundant surface structures covalently anchored to peptidoglycan and represent promising vaccine candidates for several streptococcal pathogens. It was previo...

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Main Authors: Yao Shi, Göran Widmalm, Natalia Korotkova, Adrian Molenaar, Mark A. Holmes, Scott McDougall, Jetta J. E. Bijlsma, Nina M. van Sorge, Lindert Benedictus
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Veterinary Research
Subjects:
Rhamnose-rich polysaccharides
glycerol phosphate
Streptococcus uberis
immunogenicity
bovine mastitis
bacterial cell wall
Online Access:https://doi.org/10.1186/s13567-025-01574-0
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https://doi.org/10.1186/s13567-025-01574-0

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