Low-dose radiation ameliorates doxorubicin-induced renal injury via reducing oxidative stress and protecting mitochondrial function.

Low-dose radiation ameliorates doxorubicin-induced renal injury via reducing oxidative stress and protecting mitochondrial function.

Doxorubicin (DOX) is a well-established chemotherapy drug, but its clinical application is restricted due to significant tissue toxicity, of which nephrotoxicity is a serious adverse reaction. Low-dose radiation (LDR) exerts effects through stimulating diverse cell and molecular mechanisms, which ha...

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Main Authors: Mengmeng Chen, Kang He, Kai Wang, Yibo Cai, Zhaohui Ying, Xueting Li, Yating Liu, Liting Xiang, Pingping Yang, Hongjuan Wu, Jian Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0313649
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https://doi.org/10.1371/journal.pone.0313649

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