Current Developments in Pt(IV) Prodrugs Conjugated with Bioactive Ligands

To overcome the side effects of and resistance to cisplatin, a variety of Pt(IV) prodrugs were designed and synthesized via different modifications including combination with lipid chains to increase hydrophobicity, conjugation with short peptide chains or nanoparticles to improve drug delivery, or...

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Bibliographic Details
Main Authors: Xuejiao Li, Yahong Liu, Hongqi Tian
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Bioinorganic Chemistry and Applications
Online Access:http://dx.doi.org/10.1155/2018/8276139
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