SARS-CoV-2 Protein Deposition Enhances Renal Complement Activation and Aggravates Kidney Injury in Membranous Nephropathy After COVID-19

SARS-CoV-2 Protein Deposition Enhances Renal Complement Activation and Aggravates Kidney Injury in Membranous Nephropathy After COVID-19

Introduction: COVID-19 has been reported to be associated with the occurrence and recurrence of membranous nephropathy (MN). The clinicopathological characteristics and complement system activation of MN after COVID-19 are unclear. Methods: A total of 38 patients with biopsy-proven MN who developed...

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Main Authors: Guoqin Wang, Lei Yang, Xiaoyi Xu, Weiyi Guo, Lijun Sun, Yanyan Wang, Wenrong Cheng, Nan Ye, Lingqiang Kong, Xiaoyi Zhao, Hong Cheng
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Kidney International Reports
Subjects:
complement
coronavirus disease 2019
factor H
membranous nephropathy
severe acute respiratory syndrome corona virus 2
the alternative pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024924018783
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