Exploring the antibacterial potential of Clidemia hirta leaf extract against the pathogenicity of Pseudomonas aeruginosa: in vitro and in silico approaches

Exploring the antibacterial potential of Clidemia hirta leaf extract against the pathogenicity of Pseudomonas aeruginosa: in vitro and in silico approaches

BackgroundMultidrug-resistant bacterial pathogen P. aeruginosa has emerged as a significant global health challenge, underscoring the urgent need to identify and develop alternative therapeutic agents including plant natural products. In this study, the extract from Clidemia hirta plant extract was...

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Main Authors: Vignesh Murugesan, Pargovan Palanivel, Gokul Ramesh, Dwarakesh Ganesh, Helan Soundra Rani Michael, Shivakumar Bandhumy Lingam, Rathish Kumar Sivaraman
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
Subjects:
Clidemia hirta
Pseudomonas aeruginosa
antibacterial activity
pathogenicity
penicillium binding protein
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1555542/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1555542/full

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