The interaction between ferroptosis and myocardial ischemia–reperfusion injury: molecular mechanisms and potential therapeutic targets

Abstract Myocardial ischemia–reperfusion injury (MIRI) is a common fatal event in cardiovascular diseases. Oxidative stress, energy metabolism disorders, and inflammatory responses that occur during this process cause severe damage to myocardial cells. Ferroptosis is a novel form of cell death close...

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Bibliographic Details
Main Authors: Tiantian Zhang, Yue Han, Yongcheng Wang, Xiaoyu Wang, Mingchen Zhao, Ziyang Cheng, Shiliang Zhang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:European Journal of Medical Research
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Online Access:https://doi.org/10.1186/s40001-025-02851-6
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