Targeting VCAM-1 with chimeric antigen receptor and regulatory T cell for abdominal aortic aneurysm treatment

Abstract Abdominal aortic aneurysm (AAA) is a life-threatening condition characterized by the dilation of the abdominal aorta, leading to a high risk of rupture. Current treatment options are limited, particularly for patients ineligible for surgical interventions. This study explores a novel immuno...

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Bibliographic Details
Main Authors: Qingwei Gang, Yu Lun, Xiaoxu Zhang, Jamol Uzokov, Han Jiang, Yuchen He, Shikai Shen, Shiyue Wang, Philipp Erhart, Dittmar Böckler, Yuemeng Li, Yanshuo Han, Jian Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08604-9
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