Investigating the causal links between inflammatory cytokines and scoliosis through bidirectional Mendelian randomization analysis

Investigating the causal links between inflammatory cytokines and scoliosis through bidirectional Mendelian randomization analysis

Abstract Background Scoliosis, characterized by a lateral curvature of the spine, affects millions globally. The role of inflammatory cytokines in the pathogenesis of scoliosis is increasingly acknowledged, yet their causal relationships remain poorly defined. Aims This study aims to explore the gen...

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Main Authors: Muradil Mardan, Mardan Mamat, Parhat Yasin, Xiaoyu Cai, Huoliang Zheng, Qingyin Xu, Shaokuan Song, Bo Li, Hao Cai, Pengbo Chen, Zeyu Lu, Shahna Omar, Shengdan Jiang, Leisheng Jiang, Xin‐feng Zheng
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:JOR Spine
Subjects:
causal
genetic
GWAS
inflammatory factors
Mendelian randomization
scoliosis
Online Access:https://doi.org/10.1002/jsp2.70019
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https://doi.org/10.1002/jsp2.70019

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