Consistency of Restricted Maximum Likelihood Estimators in High-Dimensional Kernel Linear Mixed-Effects Models with Applications in Estimating Genetic Heritability

Restricted maximum likelihood (REML) estimators are commonly used to obtain unbiased estimators for the variance components in linear mixed models. In modern applications, particularly in genomic studies, the dimension of the design matrix with respect to the random effects can be high. Motivated by...

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Bibliographic Details
Main Authors: Xiaoxi Shen, Qing Lu
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Mathematics
Subjects:
Online Access:https://www.mdpi.com/2227-7390/13/15/2363
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