Prediction of response to neoadjuvant chemotherapy in patients with muscle-invasive urothelial bladder cancer: role of immune-related gene expression

Prediction of response to neoadjuvant chemotherapy in patients with muscle-invasive urothelial bladder cancer: role of immune-related gene expression

Abstract This prospective study aimed at investigating the role of immune-related gene expression (GATA3, METTL3, ERCC2, PD-L1 and IFN-γ) in the prediction of response to platinum-based neoadjuvant chemotherapy (NAC) in treatment of muscle-invasive bladder cancer (MIBC). A total of 112 patients rece...

Full description

Saved in:
Bibliographic Details
Main Authors: Hadeer Mahmoud, Abeer M. Abd El-Aziz, Osama Ezzat, Hany Ibrahim Kenawy, Ahmed A. Shokeir
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Cancer Immunology, Immunotherapy
Subjects:
Bladder cancer
Neoadjuvant chemotherapy
Gene expression
Immunohistochemistry
Online Access:https://doi.org/10.1007/s00262-025-04135-8
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1007/s00262-025-04135-8

Similar Items