Anti-RBD immunoglobulin levels and their predictive value for SARS-CoV-2 neutralization

Anti-RBD immunoglobulin levels and their predictive value for SARS-CoV-2 neutralization

ABSTRACT A large number of studies have demonstrated that anti-receptor-binding domain (RBD)-binding antibody titers correlate with SARS-CoV-2 neutralization and protection from the disease. Unlike live virus neutralization assays, antibody-binding assays are easier to perform, require lower biosafe...

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Bibliographic Details
Main Authors: Sabine Lichtenegger, Sissy Therese Sonnleitner, Sabine Saiger, Andrea Zauner, Melina Hardt, Barbara Kleinhappl, Gabriel E. Wagner, Ivo Steinmetz
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:Microbiology Spectrum
Subjects:
SARS-CoV-2
hybrid immunization
neutralization assay
anti-RBD binding antibodies
correlate of protection
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02148-24
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https://journals.asm.org/doi/10.1128/spectrum.02148-24

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