Purification and Characterization of Endoglucanase from local isolate of Aspergillus flavus

Endoglucanase produced from Aspergillus flavus was purified by several steps including precipitation with 25 % ammonium sulphate followed by Ion –exchange chromatography, the obtained specific activity was 377.35 U/ mg protein, with a yield of 51.32 % .This step was followed by gel filtration chroma...

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Main Author: Baghdad Science Journal
Format: Article
Language:English
Published: University of Baghdad, College of Science for Women 2013-09-01
Series:مجلة بغداد للعلوم
Online Access:http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2594
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author Baghdad Science Journal
author_facet Baghdad Science Journal
author_sort Baghdad Science Journal
collection DOAJ
description Endoglucanase produced from Aspergillus flavus was purified by several steps including precipitation with 25 % ammonium sulphate followed by Ion –exchange chromatography, the obtained specific activity was 377.35 U/ mg protein, with a yield of 51.32 % .This step was followed by gel filtration chromatography (Sepharose -6B), when a value of specific activity was 400 U/ mg protein, with a yield of 48 %. Certain properties of this purified enzyme were investigated, the optimum pH of activity was 7 and the pH of its stability was 4.5, while the temperature stability was 40 °C for 60 min. The enzyme retained 100% of its original activity after incubation at 40 °C for 60 min; the optimum temperature for enzyme activity was 40 °C.
format Article
id doaj-art-82e41efa693344a2921a16bb965dff5c
institution Kabale University
issn 2078-8665
2411-7986
language English
publishDate 2013-09-01
publisher University of Baghdad, College of Science for Women
record_format Article
series مجلة بغداد للعلوم
spelling doaj-art-82e41efa693344a2921a16bb965dff5c2025-08-20T03:57:03ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862013-09-0110310.21123/bsj.10.3.844-853Purification and Characterization of Endoglucanase from local isolate of Aspergillus flavusBaghdad Science JournalEndoglucanase produced from Aspergillus flavus was purified by several steps including precipitation with 25 % ammonium sulphate followed by Ion –exchange chromatography, the obtained specific activity was 377.35 U/ mg protein, with a yield of 51.32 % .This step was followed by gel filtration chromatography (Sepharose -6B), when a value of specific activity was 400 U/ mg protein, with a yield of 48 %. Certain properties of this purified enzyme were investigated, the optimum pH of activity was 7 and the pH of its stability was 4.5, while the temperature stability was 40 °C for 60 min. The enzyme retained 100% of its original activity after incubation at 40 °C for 60 min; the optimum temperature for enzyme activity was 40 °C.http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2594
spellingShingle Baghdad Science Journal
Purification and Characterization of Endoglucanase from local isolate of Aspergillus flavus
مجلة بغداد للعلوم
title Purification and Characterization of Endoglucanase from local isolate of Aspergillus flavus
title_full Purification and Characterization of Endoglucanase from local isolate of Aspergillus flavus
title_fullStr Purification and Characterization of Endoglucanase from local isolate of Aspergillus flavus
title_full_unstemmed Purification and Characterization of Endoglucanase from local isolate of Aspergillus flavus
title_short Purification and Characterization of Endoglucanase from local isolate of Aspergillus flavus
title_sort purification and characterization of endoglucanase from local isolate of aspergillus flavus
url http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2594
work_keys_str_mv AT baghdadsciencejournal purificationandcharacterizationofendoglucanasefromlocalisolateofaspergillusflavus