Tracking chondrocyte-to-fibroblast transformation via changes in cell electrophysiology
Abstract Cultured chondrocytes have potential for cartilage regeneration to treat degenerative diseases. However, when explanted chondrocytes are cultured in monolayer, they are known to dedifferentiate over time, adopting a more fibroblastic phenotype. This greatly impacts both research and potenti...
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| Main Authors: | Krista S. P. Clarke, Rebecca Lewis, Michael Pycraft Hughes, Fatima H. Labeed |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-98958-1 |
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