Carboxypeptidase Y activity and maintenance is modulated by a large helical structure

Yeast carboxypeptidase Y (CPY) is a serine protease with broad substrate specificity. Structurally, CPY belongs to the α/β hydrolase fold family and contains characteristic large helices, termed the V‐shape helix, above the active site cavity. Four intramolecular disulfide bonds are located in and a...

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Bibliographic Details
Main Authors: Mai Makino, Takehiko Sahara, Naoki Morita, Hiroshi Ueno
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12686
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