The treatment of primary CoQ deficiency requires the targeting of multiple pathogenic mechanisms

Abstract Background Primary coenzyme Q (CoQ) deficiency is a severe mitochondrial disorder characterized by diverse clinical manifestations due to multiple pathomechanisms. Although CoQ10 supplementation remains the standard treatment, its therapeutic efficacy is limited by poor bioavailability and...

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Bibliographic Details
Main Authors: Pilar González-García, Laura Jiménez-Sánchez, Julia Corral-Sarasa, Sergio López-Herrador, Sara Torres-Rusillo, María Elena Díaz-Casado, Luis C. López
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-01000-8
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