Establishment of an experimental model of canine apocrine gland anal sac adenocarcinoma organoid culture using a three-dimensional culture method

Establishment of an experimental model of canine apocrine gland anal sac adenocarcinoma organoid culture using a three-dimensional culture method

Abstract Canine apocrine gland anal sac adenocarcinoma (AGASACA) is a rare, malignant tumor in dogs. To date, few cell lines are available and used to establish the current treatment protocols. Organoids are three-dimensional cell cultures derived mainly from stem cells and can reproduce tissueʼs ep...

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Main Authors: Yuko Nagashima, Haru Yamamoto, Mohamed Elbadawy, Yusuke Ishihara, Issei Tsurukami, Amira Abugomaa, Masahiro Kaneda, Hideyuki Yamawaki, Tatsuya Usui, Kazuaki Sasaki
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Canine
Apocrine gland anal sac adenocarcinoma
AGASACA
Organoids
Drug sensitivity
Online Access:https://doi.org/10.1038/s41598-025-90623-x
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https://doi.org/10.1038/s41598-025-90623-x

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