A Case of Histiocytic Sarcoma Arising from Mycosis Fungoides

Histiocytic sarcoma (HS) is an uncommon malignant neoplasm arising from mature histiocytes and most commonly characterized by the immunophenotypic expression of CD68, CD163, or lysozyme. Although rare, HS arising as a second primary malignancy following hematolymphoid neoplasms has been reported. To...

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Main Authors: Ethan A. Burns, Cesar Gentille, Saro Kasparian, Sai Ravi Pingali
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2019/7834728
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author Ethan A. Burns
Cesar Gentille
Saro Kasparian
Sai Ravi Pingali
author_facet Ethan A. Burns
Cesar Gentille
Saro Kasparian
Sai Ravi Pingali
author_sort Ethan A. Burns
collection DOAJ
description Histiocytic sarcoma (HS) is an uncommon malignant neoplasm arising from mature histiocytes and most commonly characterized by the immunophenotypic expression of CD68, CD163, or lysozyme. Although rare, HS arising as a second primary malignancy following hematolymphoid neoplasms has been reported. To our knowledge, this is the first reported case of HS occurring as a second primary malignancy in a patient with mycosis fungoides (MF), with the retained immunophenotype markers CD30 and CD4.
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institution Kabale University
issn 2090-6560
2090-6579
language English
publishDate 2019-01-01
publisher Wiley
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series Case Reports in Hematology
spelling doaj-art-826ba486d756441699a618ec0118c4362025-02-03T07:24:39ZengWileyCase Reports in Hematology2090-65602090-65792019-01-01201910.1155/2019/78347287834728A Case of Histiocytic Sarcoma Arising from Mycosis FungoidesEthan A. Burns0Cesar Gentille1Saro Kasparian2Sai Ravi Pingali3Houston Methodist Hospital, Department of Medicine, 6550 Fannin St, Ste 1101, Houston, TX 77030, USAHouston Methodist Cancer Center, 6445 Main St Floor 24, Houston, TX 77030, USAHouston Methodist Hospital, Department of Medicine, 6550 Fannin St, Ste 1101, Houston, TX 77030, USAHouston Methodist Cancer Center, 6445 Main St Floor 24, Houston, TX 77030, USAHistiocytic sarcoma (HS) is an uncommon malignant neoplasm arising from mature histiocytes and most commonly characterized by the immunophenotypic expression of CD68, CD163, or lysozyme. Although rare, HS arising as a second primary malignancy following hematolymphoid neoplasms has been reported. To our knowledge, this is the first reported case of HS occurring as a second primary malignancy in a patient with mycosis fungoides (MF), with the retained immunophenotype markers CD30 and CD4.http://dx.doi.org/10.1155/2019/7834728
spellingShingle Ethan A. Burns
Cesar Gentille
Saro Kasparian
Sai Ravi Pingali
A Case of Histiocytic Sarcoma Arising from Mycosis Fungoides
Case Reports in Hematology
title A Case of Histiocytic Sarcoma Arising from Mycosis Fungoides
title_full A Case of Histiocytic Sarcoma Arising from Mycosis Fungoides
title_fullStr A Case of Histiocytic Sarcoma Arising from Mycosis Fungoides
title_full_unstemmed A Case of Histiocytic Sarcoma Arising from Mycosis Fungoides
title_short A Case of Histiocytic Sarcoma Arising from Mycosis Fungoides
title_sort case of histiocytic sarcoma arising from mycosis fungoides
url http://dx.doi.org/10.1155/2019/7834728
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