Microenvironment-responsive living hydrogel containing engineered probiotic for treatment of massive bone defects

Microenvironment-responsive living hydrogel containing engineered probiotic for treatment of massive bone defects

Self-activating and microenvironment-responsive biomaterials for tissue regeneration would address the escalating need for bone grafting, but remain challenging. The emergence of microbial living therapeutics offers vast potential in regenerative medicine, as genetically engineered probiotics posses...

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Bibliographic Details
Main Authors: Haoyu Fang, Yanyi Wang, Li Li, Xiaotong Qin, Daoyu Zhu, Pei Liu, Qianhao Yang, Youshui Gao, Zhongmin Shi, Xin Ma, Chao Zhong, Yixuan Chen
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-08-01
Series:Bioactive Materials
Subjects:
Living hydrogel
Bacterial engineering
Smart biomaterial
Sensing-reporting
Regenerative medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X25001665
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