Molecular analysis of immune checkpoint inhibitor associated erythema nodosum-like toxicity

Molecular analysis of immune checkpoint inhibitor associated erythema nodosum-like toxicity

PurposeImmune checkpoint inhibitors (ICIs) are increasingly used to treat advanced malignancy but can induce immune-related adverse events (irAE). The mechanisms behind these sporadic and sometimes life-threatening irAEs remain largely unexplored. Here, we present a case report and in-depth molecula...

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Bibliographic Details
Main Authors: Xiaopeng Sun, Margaret L. Axelrod, Paula I. Gonzalez-Ericsson, Violeta Sanchez, Yu Wang, Jonathan L. Curry, Elizabeth J. Phillips, Yaomin Xu, Douglas B. Johnson, Justin M. Balko
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
immunotherapy
melanoma
irAE
erythema nodosum (EN)
autoimmunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1542499/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1542499/full

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