Effects of di(2-ethylhexyl) phthalate on glucose homeostasis in rats due to impaired autophagy flux of islet β cells mediated by oxidative stress

Effects of di(2-ethylhexyl) phthalate on glucose homeostasis in rats due to impaired autophagy flux of islet β cells mediated by oxidative stress

BackgroundDi(2-ethylhexyl) phthalate (DEHP) is the most prevalent environmental endocrine disruptor among phthalate acid esters (PAEs) worldwide. Previous studies have indicated that exposure to DEHP may disrupt glucose metabolism.ObjectiveTo investigate the impact of DEHP on glucose homeostasis in...

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Bibliographic Details
Main Authors: Hongyang ZHOU, Yuting HU, Xue CHEN, Yunqiang ZHOU, Liping LI, Ling LI, Herong LIU
Format: Article
Language:English
Published: Editorial Committee of Journal of Environmental and Occupational Medicine 2025-06-01
Series:环境与职业医学
Subjects:
di(2-ethylhexyl) phthalate
oxidative stress
autophagy
apoptosis
glucose homeostasis
Online Access:http://www.jeom.org/article/cn/10.11836/JEOM24601
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http://www.jeom.org/article/cn/10.11836/JEOM24601

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