Speeding up drug susceptibility testing in Mycobacterium tuberculosis using RNA biomarkersResearch in context

Speeding up drug susceptibility testing in Mycobacterium tuberculosis using RNA biomarkersResearch in context

Summary: Background: Efficient management of drug-resistant tuberculosis relies on fast diagnostics. To accelerate phenotypic drug susceptibility testing [pDST] for Mycobacterium tuberculosis [TB], we introduce TRACeR-TB, a test that infers drug resistance from antibiotic-specific mRNA biomarkers....

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Main Authors: Amandine Sury, Margo Maex, Alain Baulard, Roby P. Bhattacharyya, Stéphanie Depickère, Deborah T. Hung, Paul Cos, Fadel Sayes, Wafa Frigui, Roland Brosch, Vanessa Mathys, Elizabeth M. Streicher, Frederik De Keersmaeker, Leen Rigouts, Pieter-Jan Ceyssens, An Van den Bossche
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:EBioMedicine
Subjects:
Tuberculosis
Antimicrobial resistance
Diagnosis
RNA
Biomarkers
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396425000556
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http://www.sciencedirect.com/science/article/pii/S2352396425000556

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