The effects of microencapsulated hot chili pepper on the blood metabolites and physiological parameters of dairy cows

Background and Aim: The administration of hot chili pepper in cattle nutrition has been suggested to influence immune responses, antioxidant activities, and physiological parameters. This study aimed to evaluate the effects of microencapsulated hot chili pepper (MCP) supplementation on blood metabol...

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Main Authors: Mónica Madrigal-Valverde, Marcus Vínicius Galvão Loiola, José Esler Freitas Junior, Murilo Ramos Santiago, Lara Lôbo Dantas, Artur Azevedo Menezes, Sandro Percário, Everton Luiz Pompeu Varela, Eduardo Costa, Endrigo Adonis Braga de Araujo, Rodrigo Freitas Bittencourt
Format: Article
Language:English
Published: Veterinary World 2025-04-01
Series:Veterinary World
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Online Access:https://www.veterinaryworld.org/Vol.18/April-2025/16.pdf
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author Mónica Madrigal-Valverde
Marcus Vínicius Galvão Loiola
José Esler Freitas Junior
Murilo Ramos Santiago
Lara Lôbo Dantas
Artur Azevedo Menezes
Sandro Percário
Everton Luiz Pompeu Varela
Eduardo Costa
Endrigo Adonis Braga de Araujo
Rodrigo Freitas Bittencourt
author_facet Mónica Madrigal-Valverde
Marcus Vínicius Galvão Loiola
José Esler Freitas Junior
Murilo Ramos Santiago
Lara Lôbo Dantas
Artur Azevedo Menezes
Sandro Percário
Everton Luiz Pompeu Varela
Eduardo Costa
Endrigo Adonis Braga de Araujo
Rodrigo Freitas Bittencourt
author_sort Mónica Madrigal-Valverde
collection DOAJ
description Background and Aim: The administration of hot chili pepper in cattle nutrition has been suggested to influence immune responses, antioxidant activities, and physiological parameters. This study aimed to evaluate the effects of microencapsulated hot chili pepper (MCP) supplementation on blood metabolites, antioxidant capacity, and physiological parameters in crossbred dairy cows, contributing novel insights into metabolic and physiological adaptations under tropical production systems. Materials and Methods: Twenty-four crossbred lactating cows (Bos taurus × Bos indicus); average body weight 447.8 ± 89.6 kg; 53.54 ± 11.8 days in milk; average daily milk production 6.34 ± 1.91 L/cow/day) were randomly divided into two groups: A control group without additives and a treatment group supplemented with MCP (1,000 mg/cow/day) for 42 days. Blood samples were collected weekly for hematological analysis, biochemical evaluations, and oxidative stress biomarkers (2,2-diphenyl-1-picrylhydrazyl [DPPH], thiobarbituric acid reactive substances [TBARS], and trolox equivalent antioxidant capacity [TEAC]). Physiological measurements, including body condition score, heart rate, respiratory frequency, and urine pH, were also assessed weekly. Data were statistically analyzed using mixed-model procedures with repeated measures over time. Results: Significant interactions between treatment and time were observed for hematocrit, red blood cells, and hemoglobin (p < 0.05), indicating physiological adaptations potentially related to increased water intake. Serum albumin levels were significantly lower in MCP-supplemented cows compared to controls (p = 0.006), suggesting a modulation of lipid transport mechanisms. Temporal variations significantly affected 75% of hematological parameters and 83% of biochemical parameters. Although antioxidant parameters (DPPH, TBARS, TEAC) did not differ significantly between groups, notable temporal changes were observed (p < 0.05). Physiological parameters showed significant temporal variations but no consistent effects due to MCP supplementation. Conclusion: Supplementation of dairy cows with MCP significantly impacted hematological parameters and serum albumin levels, revealing potential metabolic adjustments involving lipid transport and hydration status. However, oxidative stress markers and physiological parameters remained largely unaffected by the supplementation. These findings support the potential regulatory role of MCP in dairy cow metabolism, emphasizing its relevance as a dietary additive in tropical livestock production systems.
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spelling doaj-art-822aeda346b040e09fd4a7e1fe0a630c2025-08-20T02:24:54ZengVeterinary WorldVeterinary World0972-89882231-09162025-04-0118490791710.14202/vetworld.2025.907-917The effects of microencapsulated hot chili pepper on the blood metabolites and physiological parameters of dairy cowsMónica Madrigal-Valverde0https://orcid.org/0000-0002-4688-0627Marcus Vínicius Galvão Loiola1https://orcid.org/0000-0003-2997-4397José Esler Freitas Junior2https://orcid.org/0000-0003-1559-0149Murilo Ramos Santiago3https://orcid.org/0009-0002-0271-2098Lara Lôbo Dantas4https://orcid.org/0009-0004-6099-7380Artur Azevedo Menezes5https://orcid.org/0000-0001-6213-3106Sandro Percário6https://orcid.org/0000-0002-9528-0361Everton Luiz Pompeu Varela7https://orcid.org/0000-0001-9710-3791Eduardo Costa8https://orcid.org/0000-0001-9980-0048Endrigo Adonis Braga de Araujo9https://orcid.org/0000-0003-4962-5637Rodrigo Freitas Bittencourt10https://orcid.org/0000-0002-0341-2073Agronomy School, CTLSC, Tecnological Institute of Costa Rica (Instituto Tecnológico de Costa Rica) Costa Rica, 223-21001; Área académica del Doctorado en Ciencias Naturales para el Desarrollo, Campus Tecnológico Local San Carlos, Instituto Tecnológico de Costa Rica, San Carlos, Costa Rica, 223-21001; Doctorado en Ciencia Naturales de para el Desarrollo (DOCINADE), Instituto Tecnológico de Costa Rica, Universidad Nacional, Universidad Estatal a Distancia, Costa Rica.School of Veterinary Medicine and Animal Science, Federal University of Bahia, Salvador, Brasil, 40170-110.School of Veterinary Medicine and Animal Science, Federal University of Bahia, Salvador, Brasil, 40170-110.School of Veterinary Medicine and Animal Science, Federal University of Bahia, Salvador, Brasil, 40170-110.School of Veterinary Medicine and Animal Science, Federal University of Bahia, Salvador, Brasil, 40170-110.School of Veterinary Medicine and Animal Science, Federal University of Bahia, Salvador, Brasil, 40170-110.Programa de Pós-graduação em Biodiversidade e Biotecnologia da Rede BIONORTE, Brasil.Programa de Pós-graduação em Biodiversidade e Biotecnologia da Rede BIONORTE, Brasil.School of Veterinary Medicine and Animal Science, Federal University of Bahia, Salvador, Brasil, 40170-110.School of Veterinary Medicine and Animal Science, Federal University of Bahia, Salvador, Brasil, 40170-110.School of Veterinary Medicine and Animal Science, Federal University of Bahia, Salvador, Brasil, 40170-110.Background and Aim: The administration of hot chili pepper in cattle nutrition has been suggested to influence immune responses, antioxidant activities, and physiological parameters. This study aimed to evaluate the effects of microencapsulated hot chili pepper (MCP) supplementation on blood metabolites, antioxidant capacity, and physiological parameters in crossbred dairy cows, contributing novel insights into metabolic and physiological adaptations under tropical production systems. Materials and Methods: Twenty-four crossbred lactating cows (Bos taurus × Bos indicus); average body weight 447.8 ± 89.6 kg; 53.54 ± 11.8 days in milk; average daily milk production 6.34 ± 1.91 L/cow/day) were randomly divided into two groups: A control group without additives and a treatment group supplemented with MCP (1,000 mg/cow/day) for 42 days. Blood samples were collected weekly for hematological analysis, biochemical evaluations, and oxidative stress biomarkers (2,2-diphenyl-1-picrylhydrazyl [DPPH], thiobarbituric acid reactive substances [TBARS], and trolox equivalent antioxidant capacity [TEAC]). Physiological measurements, including body condition score, heart rate, respiratory frequency, and urine pH, were also assessed weekly. Data were statistically analyzed using mixed-model procedures with repeated measures over time. Results: Significant interactions between treatment and time were observed for hematocrit, red blood cells, and hemoglobin (p < 0.05), indicating physiological adaptations potentially related to increased water intake. Serum albumin levels were significantly lower in MCP-supplemented cows compared to controls (p = 0.006), suggesting a modulation of lipid transport mechanisms. Temporal variations significantly affected 75% of hematological parameters and 83% of biochemical parameters. Although antioxidant parameters (DPPH, TBARS, TEAC) did not differ significantly between groups, notable temporal changes were observed (p < 0.05). Physiological parameters showed significant temporal variations but no consistent effects due to MCP supplementation. Conclusion: Supplementation of dairy cows with MCP significantly impacted hematological parameters and serum albumin levels, revealing potential metabolic adjustments involving lipid transport and hydration status. However, oxidative stress markers and physiological parameters remained largely unaffected by the supplementation. These findings support the potential regulatory role of MCP in dairy cow metabolism, emphasizing its relevance as a dietary additive in tropical livestock production systems.https://www.veterinaryworld.org/Vol.18/April-2025/16.pdfcapsaicindairy cowslipid metabolismmicroencapsulated chili pepperphysiological responsestropical livestock systems
spellingShingle Mónica Madrigal-Valverde
Marcus Vínicius Galvão Loiola
José Esler Freitas Junior
Murilo Ramos Santiago
Lara Lôbo Dantas
Artur Azevedo Menezes
Sandro Percário
Everton Luiz Pompeu Varela
Eduardo Costa
Endrigo Adonis Braga de Araujo
Rodrigo Freitas Bittencourt
The effects of microencapsulated hot chili pepper on the blood metabolites and physiological parameters of dairy cows
Veterinary World
capsaicin
dairy cows
lipid metabolism
microencapsulated chili pepper
physiological responses
tropical livestock systems
title The effects of microencapsulated hot chili pepper on the blood metabolites and physiological parameters of dairy cows
title_full The effects of microencapsulated hot chili pepper on the blood metabolites and physiological parameters of dairy cows
title_fullStr The effects of microencapsulated hot chili pepper on the blood metabolites and physiological parameters of dairy cows
title_full_unstemmed The effects of microencapsulated hot chili pepper on the blood metabolites and physiological parameters of dairy cows
title_short The effects of microencapsulated hot chili pepper on the blood metabolites and physiological parameters of dairy cows
title_sort effects of microencapsulated hot chili pepper on the blood metabolites and physiological parameters of dairy cows
topic capsaicin
dairy cows
lipid metabolism
microencapsulated chili pepper
physiological responses
tropical livestock systems
url https://www.veterinaryworld.org/Vol.18/April-2025/16.pdf
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