Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation

Hepatic ischemia and reperfusion injury is characterized by hepatocyte apoptosis, impaired autophagy, and oxidative stress. Fenofibrate, a commonly used antilipidemic drug, has been verified to exert hepatic protective effects in other cells and animal models. The purpose of this study was to identi...

Full description

Saved in:
Bibliographic Details
Main Authors: Jie Zhang, Ping Cheng, Weiqi Dai, Jie Ji, Liwei Wu, Jiao Feng, Jianye Wu, Qiang Yu, Jingjing Li, Chuanyong Guo
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2021/6658944
Tags: Add Tag
No Tags, Be the first to tag this record!