Contraction-induced endocardial id2b plays a dual role in regulating myocardial contractility and valve formation

Biomechanical cues play an essential role in sculpting organ formation. Comprehending how cardiac cells perceive and respond to biomechanical forces is a biological process with significant medical implications that remains poorly understood. Here, we show that biomechanical forces activate endocard...

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Bibliographic Details
Main Authors: Shuo Chen, Jinxiu Liang, Jie Yin, Weijia Zhang, Peijun Jiang, Wenyuan Wang, Xiaoying Chen, Yuanhong Zhou, Peng Xia, Fan Yang, Ying Gu, Ruilin Zhang, Peidong Han
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/101151
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