Structural and mechanistic profiling of Nurr1 modulation by vidofludimus enables structure-guided ligand design
Abstract The neuroprotective transcription factor nuclear receptor related 1 (Nurr1, NR4A2) is in the focus of biomedical research for its promising neuroprotective role in Parkinson’s disease, Alzheimer’s disease, and multiple sclerosis. Its activity can be controlled by ligands offering access to...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Communications Chemistry |
| Online Access: | https://doi.org/10.1038/s42004-025-01553-8 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|