HMGB1: new biomarker and therapeutic target of autoimmune and autoinflammatory skin diseases

High-mobility group box 1 (HMGB1) is expressed in almost all human cells. During cell activation and cell death, the nucleoprotein HMGB1 can translocate to the extracellular space, thus mediating the early inflammatory response as an alarmin or damage-associated molecular pattern (DAMP). Extracellul...

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Bibliographic Details
Main Authors: Jinrong Fan, Kaiqiao He, Yonghui Zhang, Ruijing Li, Xiuli Yi, Shuli Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1569632/full
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