Aerobic oxidative bromination and iodination enabled by alloxan and ascorbic acid to mimic flavin-dependent halogenases

Abstract The fundamentally significant halogenation processes in organic synthesis heavily depend on the use of hazardous and toxic elemental halogens directly or indirectly, inevitably increasing environmental burden and leading to various production problems. Flavin-dependent halogenases (FDHs) in...

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Bibliographic Details
Main Authors: Shiqi Zhang, Guang-xun Li, Dongmei Fang, Xia Zhang, Shangjing Chen, Xin Cui, Zhuo Tang
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58904-1
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