Library-based analysis reveals segment and length dependent characteristics of defective influenza genomes.

Found in a diverse set of viral populations, defective interfering particles are parasitic variants that are unable to replicate on their own yet rise to relatively high frequencies. Their presence is associated with a loss of population fitness, both through the depletion of key cellular resources...

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Bibliographic Details
Main Authors: Marisa Mendes, Alistair B Russell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-12-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1010125&type=printable
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