Protective Antimicrobial Effect of the Potential Vaccine Created on the Basis of the Structure of the IgA1 Protease from <i>Neisseria meningitidis</i>

Protective Antimicrobial Effect of the Potential Vaccine Created on the Basis of the Structure of the IgA1 Protease from <i>Neisseria meningitidis</i>

<b>Background/Objectives:</b> IgA1 protease is one of the virulence factors of <i>Neisseria meningitidis</i>, <i>Haemophilus influenzae</i> and other pathogens causing bacterial meningitis. The aim of this research is to create recombinant proteins based on fragme...

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Main Authors: Yuri Prokopenko, Alexei Zinchenko, David Karlinsky, Olga Kotelnikova, Olga Razgulyaeva, Elena Gordeeva, Elena Nokel, Oxana Serova, Elena Kaliberda, Larisa Zhigis, Lev Rumsh, Ivan Smirnov
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Vaccines
Subjects:
<i>Neisseria meningitidis</i>
IgA1 protease
epitopes
protein structure prediction
fused proteins
meningococcal vaccine
Online Access:https://www.mdpi.com/2076-393X/12/12/1355
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