Functionalized 1,3,5-triazine-derivatives as promising anticancer agents: synthesis and cytotoxic activity <i>in vitro</i>

Functionalized 1,3,5-triazine-derivatives as promising anticancer agents: synthesis and cytotoxic activity <i>in vitro</i>

Introduction. A promising area of application of 1,3,5-triazines in medical chemistry is the development of highly effective anticancer agents. It is noteworthy that a significant cytotoxic effect may occur with 2,4,6-substituted 1,3,5-triazine derivatives containing aziridine rings as substituents....

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Main Authors: A. V. Protas, O. V. Mikolaichuk, E. A. Popova, K. V. Timoshchuk, D. N. Maistrenko, O. E. Molchanov, V. V. Sharoyko, K. N. Semenov
Format: Article
Language:Russian
Published: Academician I.P. Pavlov First St. Petersburg State Medical University 2024-10-01
Series:Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова
Subjects:
1,3,5-triazine
aziridine
dioxane
cytotoxicity
mtt assay
Online Access:https://www.sci-notes.ru/jour/article/view/1053
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