Role of Genetic Alterations in the NLRP3 and CARD8 Genes in Health and Disease

The complexity of a common inflammatory disease is influenced by multiple genetic and environmental factors contributing to the susceptibility of disease. Studies have reported that these exogenous and endogenous components may perturb the balance of innate immune response by activating the NLRP3 in...

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Bibliographic Details
Main Authors: G. V. Paramel, A. Sirsjö, K. Fransén
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2015/846782
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