Extracellular vesicles from diverse fungal pathogens induce species-specific and endocytosis-dependent immunomodulation.

Extracellular vesicles from diverse fungal pathogens induce species-specific and endocytosis-dependent immunomodulation.

Microbial pathogens generate extracellular vesicles (EVs) for intercellular communication and quorum sensing. Microbial EVs also induce inflammatory pathways within host innate immune cells. We previously demonstrated that EVs secreted by Candida albicans trigger type I interferon signaling in host...

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Main Authors: Geneva N Kwaku, Kirstine Nolling Jensen, Patricia Simaku, Daniel J Floyd, Joseph W Saelens, Christopher M Reardon, Rebecca A Ward, Kyle J Basham, Olivia W Hepworth, Tammy D Vyas, Daniel Zamith-Miranda, Joshua D Nosanchuk, Jatin M Vyas, Hannah Brown Harding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012879
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https://doi.org/10.1371/journal.ppat.1012879

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