Natriuretic peptides as novel regulators of dendritic cells-mediated inflammation

Natriuretic peptides as novel regulators of dendritic cells-mediated inflammation

Abstract Natriuretic Peptides (NPs), including atrial (ANP) and brain (BNP) types, exert pleiotropic effects in regulating immune responses via the Natriuretic Peptide Receptor-1 (NPR1), expressed across various immune cells. While NPs are established inhibitors of inflammasome activation and IL-1β...

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Main Authors: Giorgia Manni, Estevao Carlos Silva Barcelos, Doriana Ricciuti, Benedetta Pieroni, Marco Gargaro, Giulia Mencarelli, Hans Acha-Orbea, Vincenzo Nicola Talesa, Letizia Mezzasoma, Francesca Fallarino
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Cellular and Molecular Life Sciences
Subjects:
Cardiac hormones
Antigen presenting cells
Autoimmune diseases
Inflammatory diseases
Natriuretic peptide receptor antagonist
Cytokines
Online Access:https://doi.org/10.1007/s00018-025-05769-8
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https://doi.org/10.1007/s00018-025-05769-8

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