Ultrasound-generated bubbles enhance osteogenic differentiation of mesenchymal stromal cells in composite collagen hydrogels

Ultrasound-generated bubbles enhance osteogenic differentiation of mesenchymal stromal cells in composite collagen hydrogels

Hydrogels can improve the delivery of mesenchymal stromal cells (MSCs) by providing crucial biophysical cues that mimic the extracellular matrix. The differentiation of MSCs is dependent on biophysical cues like stiffness and viscoelasticity, yet conventional hydrogels cannot be dynamically altered...

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Main Authors: Somnath Maji, Mitra Aliabouzar, Carole Quesada, Anjali Chiravuri, Aidan Macpherson, Abigail Pinch, Karsyn Kazyak, Ziyad Emara, Bachir A. Abeid, Robert N. Kent, III, Firaol S. Midekssa, Man Zhang, Brendon M. Baker, Renny T. Franceschi, Mario L. Fabiilli
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-01-01
Series:Bioactive Materials
Subjects:
Ultrasound
Acoustic droplet vaporization
Collagen
Mesenchymal stromal cell
Differentiation
Mechanobiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X24004134
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http://www.sciencedirect.com/science/article/pii/S2452199X24004134

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