Oxytocin Improves Autistic Behaviors by Positively Shifting GABA Reversal Potential via NKCC1 in Early‐Postnatal‐Stage

Oxytocin Improves Autistic Behaviors by Positively Shifting GABA Reversal Potential via NKCC1 in Early‐Postnatal‐Stage

Abstract Accumulating evidence has identified disrupted oxytocin signaling in both autistic patients and animal models of autism. Nevertheless, the specific timing of the impact of oxytocin on social behavior has remained unclear. Using mouse strains from oxytocin‐Cre mice crossed with Cre‐dependent...

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Main Authors: Zi‐Hui Wang, Chang Xu, Yao‐Yao Ma, Wei‐Xuan Xue, Hao‐Yuan Wang, Lin‐Yao Fan, Chen‐Yu Zhang, Liang Li, Xiao‐Yang Zhang, Jing‐Ning Zhu, Qi‐Peng Zhang
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Advanced Science
Subjects:
autism
early postnatal stage
GABA reverse potential
NKCC1
oxytocin
Online Access:https://doi.org/10.1002/advs.202415432
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https://doi.org/10.1002/advs.202415432

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