Peripheral immune signatures associated with the risk of hepatocarcinogenesis in cirrhotic Egyptian HCV patients before and after treatment with direct-acting antivirals

Peripheral immune signatures associated with the risk of hepatocarcinogenesis in cirrhotic Egyptian HCV patients before and after treatment with direct-acting antivirals

Abstract Background Although direct-acting antivirals (DAAs) have revolutionized the management of chronic HCV, the debatable association with hepatocellular carcinoma (HCC) occurrence/recurrence has raised major concerns about their long-term use, especially in cirrhotic cases. The role of epitheli...

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Bibliographic Details
Main Authors: Reem El-Shenawy, Rehab I. Moustafa, Naiera M. Helmy, Yasmine S. El-Abd, Ashraf A. Tabll, Yasser K. Elesnawy, Heba Shawky
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Virology Journal
Subjects:
HCV-related HCC
DAA
Claudin
sCD163
Cytokines
Tight junction proteins
Online Access:https://doi.org/10.1186/s12985-024-02551-3
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https://doi.org/10.1186/s12985-024-02551-3

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