Multimodal histopathologic models stratify hormone receptor-positive early breast cancer

Multimodal histopathologic models stratify hormone receptor-positive early breast cancer

Abstract The Oncotype DX® Recurrence Score (RS) is an assay for hormone receptor-positive early breast cancer with extensively validated predictive and prognostic value. However, its cost and lag time have limited global adoption, and previous attempts to estimate it using clinicopathologic variable...

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Main Authors: Kevin M. Boehm, Omar S. M. El Nahhas, Antonio Marra, Michele Waters, Justin Jee, Lior Braunstein, Nikolaus Schultz, Pier Selenica, Hannah Y. Wen, Britta Weigelt, Evan D. Paul, Pavol Cekan, Ramona Erber, Chiara M. L. Loeffler, Elena Guerini-Rocco, Nicola Fusco, Chiara Frascarelli, Eltjona Mane, Elisabetta Munzone, Silvia Dellapasqua, Paola Zagami, Giuseppe Curigliano, Pedram Razavi, Jorge S. Reis-Filho, Fresia Pareja, Sarat Chandarlapaty, Sohrab P. Shah, Jakob Nikolas Kather
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57283-x
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https://doi.org/10.1038/s41467-025-57283-x

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