Activated/Cycling Treg Deficiency and Mitochondrial Alterations in Immunological Non-Responders to Antiretroviral Therapy

Activated/Cycling Treg Deficiency and Mitochondrial Alterations in Immunological Non-Responders to Antiretroviral Therapy

Background: Regulatory T-cells (Tregs) play a crucial role in maintaining immune homeostasis, but their dynamics are altered in a subset of people living with Human Immunodeficiency Virus (HIV) known as immunological non-responders (INRs). INRs fail to reconstitute CD4+ T-cell cou...

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Bibliographic Details
Main Authors: Konstantin Shmagel, Evgeniya Saidakova, Larisa Korolevskaya, Violetta Vlasova, Souheil-Antoine Younes
Format: Article
Language:English
Published: IMR Press 2024-12-01
Series:Frontiers in Bioscience-Landmark
Subjects:
hiv-infection
antiretroviral therapy
cd4+ t-cell reconstitution
activation/cycling
immunological non-responders
regulatory t-cells
conventional to regulatory cell ratio
mitochondrial fitness
Online Access:https://www.imrpress.com/journal/FBL/29/12/10.31083/j.fbl2912429
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https://www.imrpress.com/journal/FBL/29/12/10.31083/j.fbl2912429

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